Fluid Shear Stress Increases Neutrophil Activation via Platelet-Activating Factor

Volume: 106, Issue: 10, Pages: 2243 - 2253
Published: May 1, 2014
Abstract
Leukocyte exposure to hemodynamic shear forces is critical for physiological functions including initial adhesion to the endothelium, the formation of pseudopods, and migration into tissues. G-protein coupled receptors on neutrophils, which bind to chemoattractants and play a role in neutrophil chemotaxis, have been implicated as fluid shear stress sensors that control neutrophil activation. Recently, exposure to physiological fluid shear...
Paper Details
Title
Fluid Shear Stress Increases Neutrophil Activation via Platelet-Activating Factor
Published Date
May 1, 2014
Volume
106
Issue
10
Pages
2243 - 2253
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