CaMKII associates with CaV1.2 L‐type calcium channels via selected β subunits to enhance regulatory phosphorylation

Volume: 112, Issue: 1, Pages: 150 - 161
Published: Dec 8, 2009
Abstract
J. Neurochem. (2010) 112 , 150–161. Abstract Calcium/calmodulin‐dependent kinase II (CaMKII) facilitates L‐type calcium channel (LTCC) activity physiologically, but may exacerbate LTCC‐dependent pathophysiology. We previously showed that CaMKII forms stable complexes with voltage‐gated calcium channel (VGCC) β 1b or β 2a subunits, but not with the β 3 or β 4 subunits ( Grueter et al. 2008 ). CaMKII‐dependent facilitation of Ca V 1.2 LTCCs...
Paper Details
Title
CaMKII associates with CaV1.2 L‐type calcium channels via selected β subunits to enhance regulatory phosphorylation
Published Date
Dec 8, 2009
Volume
112
Issue
1
Pages
150 - 161
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