Transitions towards either slow‐oxidative or fast‐glycolytic phenotype can be induced in the murine WTt myogenic cell line

Contraction and energy metabolism are functions of skeletal muscles co‐regulated by still largely unknown signals. To help elucidating these interconnecting pathways, we are developing new cellular models that will allow to control the switch from a neonatal to an adult slow‐oxidative or fast‐glycolytic phenotype of myofibers, during in vitro differentiation. Thus, our purpose was to direct the differentiation of the newly characterized WTt...