Clearance of the high intestinal 18F-FDG uptake associated with metformin after stopping the drug

This study was done to determine whether interruption of metformin before 18F-FDG PET/CT imaging could prevent the increased 18F-FDG uptake in the intestine caused by this drug. Included in the study were 41 patients with known type 2 diabetes mellitus who were referred to our department for evaluation of various neoplastic diseases. Patients underwent two 18F-FDG PET/CT scans, the first while they were on metformin and the second after they had...