A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B
Abstract
Import of core histones into the nucleus is a prerequisite for their deposition onto DNA and the assembly of chromatin. Here we demonstrate that nucleosome assembly protein 1 (Nap1p), a protein previously implicated in the deposition of histones H2A and H2B, is also involved in the transport of these two histones. We demonstrate that Nap1p can bind directly to Kap114p, the primary karyopherin/importin responsible for the nuclear import of H2A...
Paper Details
Title
A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B
Published Date
Dec 1, 2002
Journal
Volume
21
Issue
23
Pages
6527 - 6538
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