Differential expression of adipokines in infrapatellar fat pad (IPFP) and synovium of osteoarthritis patients and healthy individuals

Osteoarthritis (OA) is the most common form of arthritis and a major cause of pain and disability in elders. It is characterised by cartilage loss and structural changes in the whole joint. Although some mechanisms involved in the pathogenesis of OA are more and more understood, several factors involved in the onset and progression of the disease remain elusive. Together with aging and genetic factors, obesity is an important risk factor for...