Expression and Activity of Arginase Isoenzymes During Normal and Diabetes-Impaired Skin Repair

Volume: 121, Issue: 6, Pages: 1544 - 1551
Published: Dec 1, 2003
Abstract
Within the past years, an important role for nitric oxide (NO) in skin repair has been well defined. As NO is synthesized from L-arginine by NO synthases (NOS), the availability of L-arginine might be one rate-limiting factor of NO production at the wound site. Upon injury, arginase-1 and -2 mRNA, protein, and activity were strongly induced reaching a maximum between day 3 and day 7 postwounding. Immunohistochemistry colocalized both arginases...
Paper Details
Title
Expression and Activity of Arginase Isoenzymes During Normal and Diabetes-Impaired Skin Repair
Published Date
Dec 1, 2003
Volume
121
Issue
6
Pages
1544 - 1551
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