Altered somatosensory barrel cortex refinement in the developing brain of Mecp2-null mice.
Abstract
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the methyl-CpG binding protein 2 (MeCP2) gene. In previous studies, monoaminergic dysfunctions have been detected in patients with RTT and in a murine model of RTT, the Mecp2-null mouse. Therefore, the pathogenesis of RTT is thought to involve impairments in the monoaminergic systems. However, there have been limited data showing that the impairment of monoamines leads...
Paper Details
Title
Altered somatosensory barrel cortex refinement in the developing brain of Mecp2-null mice.
Published Date
Nov 6, 2013
Journal
Volume
1537
Pages
319 - 326
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Notes
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