In Vitro Antiseptic Effects on Viability of Neuronal and Schwann Cells

Volume: 37, Issue: 2, Pages: 131 - 138
Published: Jan 1, 2012
Abstract

Background and Objective

Chlorhexidine is recommended by several anesthesiology societies for antisepsis before regional anesthesia, but there is concern it may be neurotoxic. We evaluated the cytotoxicity of chlorhexidine and povidone-iodine in human neuronal and rat Schwann cells.

Methods

Human SH-SY5Y neuroblastoma and rat RSC96 Schwann cells were incubated with serial dilutions of 2% chlorhexidine gluconate and 10%...
Paper Details
Title
In Vitro Antiseptic Effects on Viability of Neuronal and Schwann Cells
Published Date
Jan 1, 2012
Volume
37
Issue
2
Pages
131 - 138
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