Alpha-Lipoic Acid Inhibits Endoplasmic Reticulum Stress-induced Cell Death Through PI3K/Akt Signaling Pathway in FRTL5 Thyroid Cells

Volume: 43, Issue: 7, Pages: 445 - 451
Published: May 17, 2011
Abstract
Alpha-lipoic acid (ALA) has been shown to modulate cell death via PI3K/Akt signal pathway in various cells. In the present study, the effects of ALA on cell death and PI3K/Akt signal pathway linked to cell death-related proteins during endoplasmic reticulum (ER) stress in FRTL5 thyroid cells were evaluated. In FRTL5 thyroid cells, cell viability increased by ALA pretreatment in tunicamycin (TN)-treated cells. When TN was treated,...
Paper Details
Title
Alpha-Lipoic Acid Inhibits Endoplasmic Reticulum Stress-induced Cell Death Through PI3K/Akt Signaling Pathway in FRTL5 Thyroid Cells
Published Date
May 17, 2011
Volume
43
Issue
7
Pages
445 - 451
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