Genomic patterns and context specific interpretation of DNA methylation
Abstract
Methylation of CpG dinucleotides is a reversible modification of DNA that is highly prevalent throughout mammalian genomes. Recent advances generated genomic DNA methylation maps during cellular differentiation at unprecedented resolution. Combined with functional assays this revealed that dynamics in DNA methylation coincide with changes in regulatory activity and that transcription factors play an important role in shaping methylation...
Paper Details
Title
Genomic patterns and context specific interpretation of DNA methylation
Published Date
Apr 1, 2014
Volume
25
Pages
85 - 92
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