Sa1231 Two Phase Photodynamic Antimicrobial Chemotherapy (PACT) Combined With Germinant Therapy Effectively Treats Clostridium difficile and Their Spores That Are Resistant to Antibiotics

Introduction null Approximately 20% of patients with null Clostridium difficile (CD) null infection relapse after initially effective treatment. These typically occur 3–10 days after cessation of standard antibiotic therapy with vancomycin or metronidazole. Some patients relapse 2 or even 3 times, each requiring additional courses of antibiotics. The general consensus is that relapse occurs either because null CD null had not been completely...