Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Volume: 17, Issue: 12, Pages: 1685 - 1691
Published: Dec 1, 2011
Abstract
Makoto Mitsunaga et al. have developed a new form of molecular-targeted cancer therapy that provides an alternative to current photodynamic approaches where damage to surrounding healthy cells and tissues can be a problem. They use a target-specific photosensitizer based on a near-infrared phthalocyanine dye, which is conjugated to monoclonal antibodies targeting human epidermal growth factor receptors (HER1 and HER2). Selective treatment using...
Paper Details
Title
Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules
Published Date
Dec 1, 2011
Volume
17
Issue
12
Pages
1685 - 1691
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