l-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders
Abstract
In recent years increasing evidence has emerged suggesting that oxidative stress is involved in the pathophysiology of a number of inherited metabolic disorders. However the clinical use of classical antioxidants in these diseases has been poorly evaluated and so far no benefit has been demonstrated. l-Carnitine is an endogenous substance that acts as a carrier for fatty acids across the inner mitochondrial membrane necessary for subsequent...
Paper Details
Title
l-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders
Published Date
Jan 1, 2014
Journal
Volume
533
Issue
2
Pages
469 - 476
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History