IgE and mast cells in allergic disease
Abstract
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to think of them in other contexts. However, a large body of evidence now suggests that both IgE and mast cells are also key drivers of the long-term pathophysiological changes and tissue remodeling associated with chronic allergic inflammation in asthma and other...
Paper Details
Title
IgE and mast cells in allergic disease
Published Date
May 1, 2012
Journal
Volume
18
Issue
5
Pages
693 - 704
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History