Scedosporium apiospermum post-traumatic cranial infection

Published on Jan 1, 2002in Brain Injury2.311
路 DOI :10.1080/02699050110119808
Claudio Farina18
Estimated H-index: 18
,
Marco Arosio3
Estimated H-index: 3
+ 1 AuthorsMohamed Amer1
Estimated H-index: 1
Source
Abstract
Scedosporium apiospermum is an environmental mould. Human infection caused by this organism is described more and more. However, only few case reports demonstrate its role as a telluric contaminant in patients affected by traumatism. A case is reported here of a severe post traumatic infection by S. apiospermum in an immunocompetent young man. Surgical drainage associated with systemic therapy was successful.
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The genus Scedosporium contains two medically significant species of emerging mycotic agents, S apiospermum and S prolificans, which have received scant attention. Scedosporium apiospermum is the anamorph, or asexual state, of the cosmopolitan fungus Pseudallescheria boydii, with both sharing the same risk factors for infection, clinical spectrum, and histopathologic features. Scedosporium prolificans is a recently recognized agent of bone, soft tissue, and joint infections that occurs with high...
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Deep Infections Caused byScedosporium prolificans:A Report on 16 Cases in Spain and a Review of the Literature Juan Berenguer;Juan Rodriguez-Tudela;Carlos Richard;Maria Alvarez;Miguel Sanz;Lourdes Gaztelurrutia;Josefina Ayats;Joaquin Martinez-Suarez; Medicine
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: Corneal scrapings from 698 clinically suspected cases of mycotic keratitis were investigated for evidence of fungal infection. Of these, 322 were found to be positive by direct examination and/or culture. The infection was predominantly seen in the age group 21-50. Men were more frequently affected than women. Majority of the patients were either agricultural workers or out door manual labourers and 66.8% of them gave a definite history of antecedent corneal trauma due to vegetable or soil mat...
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Abstract Scedosporium species are now increasingly isolated from immunocompromised and immunocompetent patients. Unfortunately, Scedosporium species infections are generally resistant to amphotericin B, and S. prolificans strains are particularly resistant to presently-available antifungal agents. Here we review the microbiology, expanding epidemiology, numerous clinical presentations, and diagnostic tools available for Scedosporium species infections. Finally, we detail the available in vitro, ...
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