Loss of photoreceptor potential from retinal progenitor cell cultures, despite improvements in survival
Abstract
Retinal degeneration (RD) results from photoreceptor apoptosis. Cell transplantation, one potential therapeutic approach, requires expandable stem cells that can form mature photoreceptors when differentiated. Freshly dissociated primary retinal cells from postnatal day 2-6 (PN2-6) mouse retina can give rise, post-transplantation, to photoreceptors in adult recipients. Unfortunately, incorporation rates are low; moreover, photoreceptor potential...
Paper Details
Title
Loss of photoreceptor potential from retinal progenitor cell cultures, despite improvements in survival
Published Date
Oct 1, 2010
Journal
Volume
91
Issue
4
Pages
500 - 512
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