Role of matrix metalloproteinases (MMPS) in periodontitis and its management

Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that mediate the degradation of extracellular matrix (ECM) macromolecules. The activity of MMPs is seen not only during normal organogenesis and wound healing, but also in pathological condition like inflammatory diseases. MMP synthesis and functions are regulated by transcriptional activation, post-transcriptional processing and by a family of endogenous inhibitors...