Adipose‐Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E2
Abstract
Objective To examine the effect of different sources of Good Manufacturing Practice clinical grade adipose‐derived mesenchymal stem cells (AD‐MSCs) on inflammatory factors in osteoarthritic (OA) chondrocytes and synoviocytes. Methods AD‐MSCs from infrapatellar Hoffa fat, subcutaneous (SC) hip fat, and SC abdominal fat were cocultured in Transwells with chondrocytes or synoviocytes. Inflammatory factors (interleukin‐1β [IL‐1β], tumor necrosis...
Paper Details
Title
Adipose‐Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E2
Published Date
Apr 23, 2013
Journal
Volume
65
Issue
5
Pages
1271 - 1281
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