Renal glomerular permselectivity and vascular endothelium

The glomerular barrier is the kidney’s physical block to the unrestricted flow of molecules from the plasma into the urinary space. Its exquisite selectivity allows solutes and water in the glomerular capillaries to pass through but it prevents the bulk of plasma proteins, most notably albumin, froom crossing. Classically the barrier consists of three components: glomerular endothelium, glomerular basement membrane and glomerular epithelium...