Immune responses and side effects of five different oil-based adjuvants in mice

Volume: 61, Issue: 2-4, Pages: 291 - 304
Published: Feb 1, 1998
Abstract
In this study, five different oil based adjuvants were compared to assess efficacy and side effects. Mice were injected subcutaneously (s.c.) or intraperitoneally (i.p.) with a weak immunogen (synthetic peptide) emulsified in Freund's adjuvant (FA), Specol, RIBI, TiterMax or Montanide ISA50. Efficacy of adjuvants was evaluated based on their properties to induce peptide specific IgG1, IgG2a and total IgG antibodies, native protein cross-reactive...
Paper Details
Title
Immune responses and side effects of five different oil-based adjuvants in mice
Published Date
Feb 1, 1998
Volume
61
Issue
2-4
Pages
291 - 304
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