Sequential Spontaneous Resolution of Acute Syphilitic Posterior Placoid Chorioretinitis

Purpose Acute syphilitic posterior placoid chorioretinitis (ASPPC) is a distinctive manifestation of ocular syphilis characterized by the development of a placoid macular deposit in the outer retina. Fundus autofluorescence descriptions suggest it may result from subretinal deposition of retinal pigment epithelium (RPE)–photoreceptor complex material and incomplete phagocytosis of outer segments. A 14-day therapy with systemic penicillin is...