Intracardiac flow dynamics regulate atrioventricular valve morphogenesis
Abstract
Valvular heart disease is responsible for considerable morbidity and mortality. Cardiac valves develop as the heart contracts, and they function throughout the lifetime of the organism to prevent retrograde blood flow. Their precise morphogenesis is crucial for cardiac function. Zebrafish is an ideal model to investigate cardiac valve development as it allows these studies to be carried out in vivo through non-invasive imaging. Accumulating...
Paper Details
Title
Intracardiac flow dynamics regulate atrioventricular valve morphogenesis
Published Date
Aug 6, 2014
Journal
Volume
104
Issue
1
Pages
49 - 60
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History