The thioredoxin antioxidant system
Abstract
The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR), and thioredoxin, is a key antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance. The Trx system provides the electrons to thiol-dependent peroxidases (peroxiredoxins) to remove reactive oxygen and nitrogen species with a fast reaction rate. Trx antioxidant functions are...
Paper Details
Title
The thioredoxin antioxidant system
Published Date
Jan 1, 2014
Volume
66
Pages
75 - 87
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