CCR6 as a possible therapeutic target in psoriasis

Volume: 14, Issue: 9, Pages: 911 - 922
Published: Jul 15, 2010
Abstract
Importance of the field: Psoriasis is a common, chronic autoimmune disease of the skin. Despite a number of effective treatments, new therapies are needed with enhanced efficacy, safety and convenience. Chemokine receptors are GPCRs that control leukocyte trafficking, and like other GPCRs, are good potential drug targets. The chemokine receptor CCR6 is expressed on the TH17 subset of CD4+ T cells, which produces IL-17A/F, IL-22, TNF-α and other...
Paper Details
Title
CCR6 as a possible therapeutic target in psoriasis
Published Date
Jul 15, 2010
Volume
14
Issue
9
Pages
911 - 922
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