Defining Requirements for Collagenase Cleavage in Collagen Type III Using a Bacterial Collagen System

Volume: 287, Issue: 27, Pages: 22988 - 22997
Published: Jun 29, 2012
Abstract
Degradation of fibrillar collagens is important in many physiological and pathological events. These collagens are resistant to most proteases due to the tightly packed triple-helical structure, but are readily cleaved at a specific site by collagenases, selected members of the matrix metalloproteinases (MMPs). To investigate the structural requirements for collagenolysis, varying numbers of GXY triplets from human type III collagen around the...
Paper Details
Title
Defining Requirements for Collagenase Cleavage in Collagen Type III Using a Bacterial Collagen System
Published Date
Jun 29, 2012
Volume
287
Issue
27
Pages
22988 - 22997
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