Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans
Abstract
Quantitative knowledge of the turnover of different leukocyte populations is a key to our understanding of immune function in health and disease. Much progress has been made thanks to the introduction of stable isotope labeling, the state-of-the-art technique for in vivo quantification of cellular life spans. Yet, even leukocyte life span estimates on the basis of stable isotope labeling can vary up to 10-fold among laboratories. We investigated...
Paper Details
Title
Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans
Published Date
Sep 26, 2013
Journal
Volume
122
Issue
13
Pages
2205 - 2212
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