A proline-rich polypeptide complex and its nonapeptide fragment inhibit nitric oxide production induced in mice
Abstract
A proline-rich polypeptide complex (PRP) isolated from ovine colostrum shows immunoregulatory and procognitive activities. It shows beneficial effects in Alzheimer's disease (AD) patients when orally administered in the form of tablets called Colostrinin®. The mechanism of action of PRP/Colostrinin® in AD has not been yet clarified. It is known that oxidative stress and overproduction of NO may enhance neurodegenerative processes. PRP regulates...
Paper Details
Title
A proline-rich polypeptide complex and its nonapeptide fragment inhibit nitric oxide production induced in mice
Published Date
Feb 1, 2005
Journal
Volume
125
Issue
1-3
Pages
35 - 39
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