Intravitreal Aflibercept Injection for Macular Edema Resulting from Central Retinal Vein Occlusion

To evaluate the efficacy and safety of intravitreal aflibercept injections for treatment of macular edema secondary to central retinal vein occlusion (CRVO).A randomized, multicenter, double-masked phase 3 study.A total of 177 treatment-naive patients with macular edema secondary to CRVO were randomized in a 3:2 ratio.Patients received either 2-mg intravitreal aflibercept or sham injections every 4 weeks for 20 weeks. From week 24 to 48, the...