Impact of cytokines on diffuse splenic 18F-fluorodeoxyglucose uptake during positron emission tomography/computed tomography

Objectives Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic 18F-fluorodeoxyglucose (18F-FDG) uptake. In this study, we focused on cytokines to investigate interactions during this phenomenon and clarify the significance of splenic 18F-FDG uptake in PET/CT. Methods We selected 40 patients (17 women and 23 men) with cholangiocarcinoma, pancreatic cancer, or gallbladder...