Cloning and identification of a gene coding for a 26-kDa hemoglobin-binding protein from Entamoeba histolytica
Abstract
The capability of Entamoeba histolytica to use hemoglobin (Hb) as an iron source has been documented. However, the underlying mechanism to acquire iron from this source is poorly understood. In the present work, an in silico analysis in the E. histolytica genome (Pathema database) allowed us to identify a gene coding for a putative 26-kDa protein (Ehhmbp26) which contains the motifs necessary for Hb-binding. The purified Ehhmbp26 protein was...
Paper Details
Title
Cloning and identification of a gene coding for a 26-kDa hemoglobin-binding protein from Entamoeba histolytica
Published Date
Mar 1, 2009
Journal
Volume
91
Issue
3
Pages
383 - 389
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