In Situ Detection of Calcium Phosphate Clusters in Solution and Wet Amorphous Phase by Synchrotron X-ray Absorption Near-Edge Spectroscopy at Calcium K-Edge

Calcium phosphate clusters are present in both aqueous solutions and an amorphous phase during crystallization. It is a challenging task to acquire the structural information on such clusters, owing to their small size, chemical lability, and inaccessibility to most detection techniques. Here, we demonstrate the feasibility of detecting such clusters in situ by synchrotron X-ray absorption near-edge spectroscopy at calcium K-edge, a technique...