Co-existence of nemaline and cytoplasmic bodies in muscle of an infant with nemaline myopathy

Published on Dec 1, 2002in Neuropathology1.758
· DOI :10.1046/J.1440-1789.2002.00461.X
Kiyotaka Suwa7
Estimated H-index: 7
,
Masashi Mizuguchi22
Estimated H-index: 22
+ 4 AuthorsIkuya Nonaka80
Estimated H-index: 80
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Abstract
A sporadic case of congenital myopathy had severe muscle weakness of neonatal onset. Nemaline and cytoplasmic bodies were detected in muscle biopsies taken at 4 months of age. These findings were consistent with a diagnosis of nemaline myopathy (severe neonatal form). The simultaneous and abundant presence of these two types of sarcoplasmic inclusion has been found in only a few cases. However, these cases suggest that the sarcoplasmic inclusions may be formed, at least partially, by common mechanisms.
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