Functions and regulation of MUC13 mucin in colon cancer cells
Abstract
MUC13 is overexpressed and aberrantly localized in colon cancer tissue; however, the specific functions and regulation of MUC13 expression are unknown. Stable cell lines with either overexpressed or suppressed MUC13 levels were analyzed to determine cell growth, colony formation, cell migration, and cell invasion assays. The molecular mechanisms involved in MUC13 regulation were elucidated via chromatin immunoprecipitation (ChIP) and analysis of...
Paper Details
Title
Functions and regulation of MUC13 mucin in colon cancer cells
Published Date
Oct 7, 2013
Journal
Volume
49
Issue
10
Pages
1378 - 1391
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