Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage

Volume: 91, Issue: 2, Pages: 515 - 527
Published: Oct 1, 2011
Abstract
Sulfur mustard (SM, bis(2-chloroethyl)sulfide) is a bifunctional alkylating agent that causes dermal inflammation, edema and blistering. To investigate the pathogenesis of SM-induced injury, we used a vapor cup model which provides an occlusive environment in which SM is in constant contact with the skin. The dorsal skin of SKH-1 hairless mice was exposed to saturated SM vapor or air control. Histopathological changes, inflammatory markers and...
Paper Details
Title
Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage
Published Date
Oct 1, 2011
Volume
91
Issue
2
Pages
515 - 527
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