Intravitreal Aflibercept Injection for Macular Edema Due to Central Retinal Vein Occlusion

To evaluate the efficacy and safety of intravitreal aflibercept injection (IAI) for the treatment of macular edema secondary to central retinal vein occlusion (CRVO).Randomized, double-masked, phase 3 trial.A total of 188 patients with macular edema secondary to CRVO.Patients received IAI 2 mg (IAI 2Q4) (n = 114) or sham injections (n = 74) every 4 weeks up to week 24. During weeks 24 to 52, patients from both arms were evaluated monthly and...