Vitamin C: update on physiology and pharmacology
Abstract
Although ascorbic acid is an important water-soluble antioxidant and enzyme cofactor in plants and animals, humans and some other species do not synthesize ascorbate due to the lack of the enzyme catalyzing the final step of the biosynthetic pathway, and for them it has become a vitamin. This review focuses on the role of ascorbate in various hydroxylation reactions and in the redox homeostasis of subcellular compartments including mitochondria...
Paper Details
Title
Vitamin C: update on physiology and pharmacology
Published Date
Aug 1, 2009
Volume
157
Issue
7
Pages
1097 - 1110
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