Notch Inhibitors for Cancer Treatment
Abstract
Notch signaling is an evolutionarily conserved cell signaling pathway involved in cell fate during development, stem cell renewal and differentiation in postnatal tissues. Roles for Notch in carcinogenesis, in the biology of cancer stem cells and tumor angiogenesis have been reported. These features identify Notch as a potential therapeutic target in oncology. Based on the molecular structure of Notch receptor, Notch ligands and Notch...
Paper Details
Title
Notch Inhibitors for Cancer Treatment
Published Date
Aug 1, 2013
Journal
Volume
139
Issue
2
Pages
95 - 110
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Notes
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