Predictive models of toxicity in external radiotherapy

Dose‐volume modeling of late and acute toxicity in radiotherapy for prostate cancer is a rapidly evolving field of investigation. The availability of individual, 3‐dimensional dose distribution and dose‐volume histograms (DVHs) permits the quantitative assessment of dose‐volume relations for specific endpoints by investigating the correlation between individual dose‐volume data and clinical outcomes. These studies often entail a huge effort in...