Gain in Chromosome 8q Correlates with Early Progression in Hormonal Treated Prostate Cancer

Development and especially hormone refractant progression of prostate cancer are incompletely understood. Clinical studies evaluating genetic aberrations of prior therapy biopsies in correlation with progression data in patients receiving hormone therapy for prostate cancer have not been performed until now.After DNA isolation from histological sections of primary prostate cancer biopsies, comparative genomic hybridization (CGH) was performed...