Perivascular Fibroblasts Form the Fibrotic Scar after Contusive Spinal Cord Injury
Abstract
Injury to the CNS leads to formation of scar tissue, which is important in sealing the lesion and inhibiting axon regeneration. The fibrotic scar that comprises a dense extracellular matrix is thought to originate from meningeal cells surrounding the CNS. However, using transgenic mice, we demonstrate that perivascular collagen1α1 cells are the main source of the cellular composition of the fibrotic scar after contusive spinal cord injury in...
Paper Details
Title
Perivascular Fibroblasts Form the Fibrotic Scar after Contusive Spinal Cord Injury
Published Date
Aug 21, 2013
Journal
Volume
33
Issue
34
Pages
13882 - 13887
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