Polymorphisms inESR1,ESR2andHSD17B1genes are associated with fertility status in endometriosis

Objective. To investigate whether polymorphisms in genes involved in biosynthesis and signalling of sex steroids influence susceptibility to endometriosis and to infertility associated with it.Materials and methods. Patients with endometriosis (n = 150) and fertile controls (n = 199) were genotyped for polymorphisms in oestrogen receptor genes ESR1 (rs2234693 – T/C single nucleotide polymorphism (SNP), dinucleotide (TA)n repeat) and ESR2...