GC–MS-based metabolomics study of the responses to arachidonic acid in Blakeslea trispora

The potential use of arachidonic acid (AA) to enhance the production of β-carotene in Blakeslea trispora was investigated in this work. To study the mechanism of the B. trispora response to AA, we used a systematic analytical approach to investigate the changes in the B. trispora cell metabolome at different time points after AA treatment. A maximum of β-carotene production was obtained when 0.4g/l AA was added after 36h of cultivation. Gas...