Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

Nature64.80
Volume: 466, Issue: 7308, Pages: 829 - 834
Published: Aug 12, 2010
Abstract
The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial and perivascular cells. Here we demonstrate that mesenchymal stem cells (MSCs), identified using nestin expression, constitute an essential HSC niche component. Nestin(+) MSCs contain all the bone-marrow colony-forming-unit fibroblastic activity and can be propagated as non-adherent...
Paper Details
Title
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Published Date
Aug 12, 2010
Journal
Volume
466
Issue
7308
Pages
829 - 834
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.