Genomic and nongenomic effects of glucocorticoids
Abstract
The strong anti-inflammatory and immunosuppressive effects of glucocorticoids are mediated primarily by the cytosolic glucocorticoid receptors. These receptors are members of the steroid hormone receptor family, a superfamily of ligand-inducible transcription factors, and exert genomic effects that can result in increased expression of regulatory-including anti-inflammatory-proteins (transactivation), or decreased production of proinflammatory...
Paper Details
Title
Genomic and nongenomic effects of glucocorticoids
Published Date
Sep 2, 2008
Volume
4
Issue
10
Pages
525 - 533
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