Experimental emetine myopathy: enzyme histochemical, electron microscopic, and immunomorphological studies
Abstract
Ipecac, containing emetine hydrochloride, is used by patients with anorexia nervosa to induce vomiting. Its chronic usage may result in a myopathy and a cardiomyopathy, the former marked by cytoplasmic bodies. We studied myopathological changes after daily injections of female Wistar rats with emetine hydrochloride intraperitoneally for periods of 4, 5, 9, and 10 weeks. the extensor digitorum longus muscle and the soleus muscle showed core-like...
Paper Details
Title
Experimental emetine myopathy: enzyme histochemical, electron microscopic, and immunomorphological studies
Published Date
Jan 1, 1993
Journal
Volume
85
Issue
4
Pages
414 - 418
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