Atlas of the clinical genetics of human dilated cardiomyopathy

Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until now technological limitations have hindered elucidation of the contribution of all clinically relevant disease genes to DCM phenotypes in larger cohorts. We now utilized next-generation sequencing to overcome these limitations and screened all DCM disease genes in a large cohort.In this multi-centre, multi-national study, we have enrolled 639 patients with sporadic or...