The effect of periodontal therapy on serum TNF-α and HbA1c levels in type 2 diabetic patients

To determine the effect of non-surgical periodontal therapy on serum TNF-alpha and HbA1c levels in poorly and well-controlled type 2 diabetic patients.In total, 45 patients were enrolled in the study; 30 patients with type 2 diabetes mellitus with periodontitis (15 with poorly controlled diabetes, HbA1c >or= 7%, group 1A and 15 with well-controlled diabetes, HbA1c < 7%, group 1B) and 15 patients that were systemically healthy with periodontitis...