The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds.

Volume: 142, Issue: 4, Pages: 991 - 997
Published: Nov 3, 2006
Abstract
Hereditary creatine transporter deficiency causes brain damage, despite the brain having the enzymes to synthesize creatine. Such damage occurring despite an endogenous synthesis is not easily explained. This condition is incurable, because creatine may not be delivered to the brain without its transporter. Creatine-derived compounds that crossed the blood-brain barrier in a transporter-independent fashion would be useful in the therapy of...
Paper Details
Title
The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds.
Published Date
Nov 3, 2006
Volume
142
Issue
4
Pages
991 - 997
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