Reduction of image noise in low tube current dynamic CT myocardial perfusion imaging using HYPR processing: A time-attenuation curve analysis

Purpose: This study describes a HighlY constrained backPRojection (HYPR) image processing method for the reduction of image noise in low tube current time‐resolved CT myocardial perfusion scans. The effect of this method on myocardial time‐attenuation curve noise and fidelity is evaluated in an animal model, using varying levels of tube current. Methods: CT perfusion scans of four healthy pigs (42–59 kg) were acquired at 500, 250, 100, 50, 25,...